Longevity Therapy


What we have been calling old age in medicine (a constellation of age related disease processes) was re-classified as a disease by the World Health Organization in 2019. According to Doctor David Sinclair, Head of the Harvard Genetics Lab, humans’ average life expectancy in our modern technological era should be around 125 years of age. Currently the oldest verified human on the planet recently lived to be 122 years old. Sinclair and other longevity experts believe that these outliers in the population should be the norm and that further outliers should be as old as 150 or 160 years with normal, healthy brain and body functions.

NAD+ was discovered more than 100 years ago while working on its precursor Niacin – Vitamin B3 and its principles are taught in every high school biology class, but just over the last decade has it become a promising compound to not only decrease age related illness but increase total body performance and wellness in all populations.

Using NAD+ boosters, scientists in genetics labs around the globe have more than doubled the healthy life-spans of laboratory animals, creating middle-aged super animals that outperform their youthful control groups in fitness, reproductive health and neurological capabilities. Currently these same compounds are undergoing human clinical trials to determine which compounds are most quickly absorbed and used in the human cell to promote DNA repair.

There are many reasons that disease processes overwhelm people’s bodies in their senior years, but the most current literature points to modifiable proteins called Sirtuins that are required for DNA repair. Longevity experts are focusing on using our body’s own enzymes and regulatory systems to give these essential DNA repair enzymes the best chance of fighting off “old age.” Sirtuins can only function in the presence of NAD+, a coenzyme found in all living cells. As we grow older, NAD+ levels decrease because of our body’s increased requirements to repair cells due to oxidative damage and stress. Yet when we are middle-aged, we produce half of the NAD+ that we produced in our twenties, so in turn we have less NAD+ to activate this repair process. Disease-related aging is a feedback loop that prevents our natural production of the ingredients that repair our DNA.

Fortunately, NAD+ is a natural coenzyme derived from Niacin – Vitamin B3 that has been used for decades in medical science as a growth medium to produce cell cultures including treatments for damaged tissue after chemotherapy and treatments for alcoholism and drug addiction recovery. This coenzyme can be safely infused into the body where our body’s Sirtuins rapidly assimilate it for DNA repair.

Decades of abundant scientific evidence shows clear safety with intravenous NAD+ in humans.

NAD+ has multi-organ benefits in animals including improved liver, kidney, skeletal muscle, cardiac and blood vessel function, DNA repair, anticancer, immunity, neuroprotective and anti-inflammatory effects.


Metformin is a prescription diabetes medication that was discovered in 1922 by isolating a compound in the French lilac plant. It has been used successfully for the last 60 years as the primary treatment for controlling elevated blood sugar in patients with type II diabetes. It is well established in the medical community that dysregulation of insulin and blood sugar levels contribute to a myriad of disease processes and early death. Recently there has been considerable investigation into Metformin’s benefits in non-diabetic populations in prevention of disease states such as cancer, Alzheimer’s disease, heart disease and increasing longevity.

There are several mechanisms that have been shown to delay the aging process in humans, including restricting calories and altering growth hormone pathways GF/IGF  as well as activation of Sirtuins and inhibiting a gene called mTOR

Metformin has an interplay with all of these mechanisms by conserving what is called the “evolutionary advantage” or mitohormesis.  

Mitohormesis or “hormesis” is a cellular defense mechanism that is triggered during healthy levels of cellular stress, such as what happens during calorie restriction and exercise. This process is also turned on by Metformin and signaling cascades within the cells ramp up the DNA repair process, balance critical growth factors and protect the cells from harmful events.

One-third of the US population is unwittingly living in prediabetic state and one half of those over 65 have prediabetes. This is partially due to genetic factors, but contributing factors are likely elevated dietary intake of sugar and carbohydrates and lack of exercise.  

Our consultation for initiation of Metformin always includes measuring critical lab values such as HA1C levels, insulin, IGF and fasting blood glucose levels. 

Even if your levels do not indicate a prediabetic state, the safety profile of Metformin and its potential for disease prevention and increased longevity makes it a promising and valuable therapy. 

$349 – $799

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